I doubt it. There is no alternative (TINA). Assuming that we are Brexiting, nobody on the Leave side is competent enough to take over her role. And somebody on the Remain side would not be trusted.
The constitution of this Parliament means that the DUP hold the balance of power and they will not support Corbyn (due to his IRA sympathies). And Labour will not get rid of him (not for lack of trying). Thus we will have the Conservatives in power for the next few years.
The leading lights in the Conservative Party to be next Prime Minister are Bojo (really??), Jacob Rees-Mogg and Amber Rudd. I thought Amber Rudd has done a pretty good job at the Home Office, but then look at what happened to the previous occupant of that post.
So, really, for the time being, we are stuck with Theresa May.
And I believe that like the Queen, she has a sense of duty to the country (vicar's daughter and all) and will not quit unless there is a clear alternative to take over from her. Unlike mkhan2525, I do not think she is power-hungry and would go if there is a viable (Conservative) alternative.